Introduction to diagnostic test accuracy studies

Studies of diagnostic test accuracy

Definition of a diagnostic test accuracy study? o A diagnostic test accuracy study evaluates the accuracy of index test in correctly distinguishing between those with disease and those without disease compared to gold standard test. o Gold standard test is also called criterion test or reference test. o For a diagnostic test to be accurate, it should be both valid (accuracy) and reliable (preci...

Meta-analysis of Diagnostic Test Accuracy Studies

Diagnostic accuracy studies : how to report and analyse inconclusive test

The results of studies on diagnostic test accuracy are often reported as a 2×2 classification matrix, in which test results are presented as a dichotomy and a reference standard is used to categorise individuals as with or without disease. This facilitates the calculation of many popular statistics used to summarise the discriminatory performance of tests (such as sensitivity and specificity, p...

Cochrane diagnostic test accuracy reviews

In 1996, shortly after the founding of The Cochrane Collaboration, leading figures in test evaluation research established a Methods Group to focus on the relatively new and rapidly evolving methods for the systematic review of studies of diagnostic tests. Seven years later, the Collaboration decided it was time to develop a publication format and methodology for Diagnostic Test Accuracy (DTA) ...

An Introduction to Natural Experiment Studies

در دو سخن سردبیری شماره‌های قبل به مطالعات مداخله‌ای (Interventional and/or experimental studies) [1] و مطالعات نیمه تجربی (studies Quasi-experiment) [2] پرداختیم. همان جا، به این نکته اشاره کردیم که برای اندازه‌گیری کارآیی یک دارو، واکسن، برنامه بهداشت عمومی و متغیرهای دیگری از این دست، مطالعات مداخله‌ای بهترین گزینه هستند. تقسیم تصادفی و کورسازی از مؤلفه‌های اساسی یک مطالعه مداخله‌ای است [1]....